Frank Buxton was born in 1930 in Wellesley, Massachusetts and grew up in Larchmont, New York. He is a graduate of Northwestern University (B.S.) and Syracuse University (M.S.). After U.S. Army service in Korea he worked as a producer-director at WGN-TV in Chicago and WGR-TV and WBUF-TV in Buffalo. Turning to performing, Buxton performed his own stand-up comedy act at comedy clubs from coast to coast.

Frank's acting career extends from summer theatre in Three Men on a Horse (with the legendary Buster Keaton), to touring Australia for a year as Albert in Bye Bye Birdie, hosting a game show (Get the Message), movie roles in What's Up, Tiger Lily? and Overboard, and numerous TV series, movies and commercials.

He has written and directed a number of television specials and series. He created, wrote, produced and directed the Peabody Award-winning series Hot Dog for NBC-TV, which starred Woody Allen, Tom Smothers, Jonathan Winters, and JoAnne Worley. Frank was the spokesperson for Safeway Markets in Northern California and Hawaii, and his voicework includes Batfink and Garfield and Friends. He is a regular performer on radio on Jim French's Imagination Theatre, The Adventures of Harry Nile, and The Further Adventures of Sherlock Holmes.

Frank is a founding member of The Edge, Seattle's Improv Group, and he has produced and directed On The Air (re-creations of vintage radio programs) for five seasons for Island Theatre and for The Radio Enthusiasts of Puget Sound. Currently, Frank is appearing on the webcast Cookus Interruptus as Matt's father Ward, who has come for a short visit which is getting longer every day.

He is the co-author, with Bill Owen, of two volumes of radio history, Radio's Golden Age and The Big Broadcast, the latter re-published by Scarecrow Press in 1997. Also in 1997, TV Guide declared the Password episode of the TV series The Odd Couple, which Frank wrote, as the fifth greatest TV segment of all time.

A big fan of movies, Frank is on the Board of Directors of the San Francisco Silent Film Festival, and a supporter of the Port Townsend Film Festival.